Mustard Seeds

Latin name: brassica juncea L.

Common name: Mustard seeds

Cultural significance/history: archaeological evidence suggests that mustard seeds were used by humans from 3000 BC, in particular the greek philosopher Hippocrates used to used mustard seeds in poultices to relieve muscular pain. Mustard is one of the most popular spices around the world, used in India, Bangladesh, Europe, the Americas and elsewhere.

Active ingredients: Glucosinolates and Omega-3-Fatty Acids

Where it is found naturally: Foothills of the Himalayas 

uses/indications of Brassica Juncea L.: it was typically used as an Emetic and Diuretic, also topically used to treat joint and muscle pain, as well as a treatment for inflammatory diseases

Mechanism of action: glucosinolates are inactive until hydrolysed to isothiocyanates. Isothiocyanates work to disrupt bacterial and fungal cell membranes, inhibits NFk-B signalling, downregulates COX-2 TNF-a and IL-6 contributing to reducing inflammation. Omega- 3 fatty acids have numerous health benefits including reducing levels of triglycerides in the blood, helping improve brain and eye function, and reduces the risk of ischaemic stroke and heart disease. 

Pharmacokinetics: Oral/ Transdermal administration, rapidly absorbed and is then found in various organs such as the liver and the bladder, metabolised via the mercapturic acid pathway and excreted in urine 

Side effects: reduced appetite, nausea, hepatic and renal lesions, affects thyroid function by blocking iodine uptake

Sample #29/43